TLDR AGA patients have lower serum vaspin levels, which might help detect the condition early.
This study investigated serum vaspin levels in 50 patients with androgenetic alopecia (AGA) compared to 30 healthy controls. Results showed that AGA patients had significantly lower serum vaspin levels than the controls. There were no significant associations between vaspin levels and factors such as age, sex, smoking, BMI, disease duration, or family history. The study suggests that vaspin deficiency could potentially be used to detect AGA at an early stage, with a negative predictive value of 87.5% at a cutoff value of 2302.2 pigs/dl.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
11 citations,
December 2022 in “Arterial Hypertension” 
20 citations,
August 2022 in “Archives of Medical Science” The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
