The study "Association of Primary Cicatricial Alopecia with Subsequent Cardiovascular Disease" by Kim et al. (2023) explores the link between Primary Cicatricial Alopecia (PCA) and cardiovascular disease (CVD) risk, involving over 400,000 individuals from the National Health Insurance Service registry. The findings indicate that patients with PCA have an 18% increased likelihood of developing CVDs compared to controls, with specific subtypes like lichen planopilaris (LPP) showing a pronounced risk. The study suggests that chronic inflammatory diseases, such as PCA, are associated with endothelial dysfunction and increased CV risk. However, the study did not adjust for alopecia severity or exclude androgenetic alopecia, which could confound results. Despite these limitations, the research highlights a potential systemic aspect of PCA, warranting further investigation into its role in CVD risk.
38 citations,
January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
14 citations,
March 2016 in “Journal of Dermatology” Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
14 citations,
September 2016 in “Journal of Cutaneous Pathology” The document concludes that new methods improve the accuracy of diagnosing scalp alopecia and challenges the old way of classifying it.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
9 citations,
September 2016 in “Dermatologic Surgery” New LPP subtype affects vellus hairs, mimics AGA, and needs biopsy for diagnosis.
98 citations,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
11 citations,
February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
18 citations,
October 2012 in “Dermatologic Clinics” Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
