Correlating Cicatricial Alopecia and Cardiovascular Risk: Emerging Insights

    March 2024 in “ Journal of Investigative Dermatology ”
    Andrea Sechi, Antonellá Tosti
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    TLDR People with Primary Cicatricial Alopecia have a higher risk of heart disease.
    A recent study involving over 400,000 individuals highlights a significant association between primary cicatricial alopecia (PCA) and an increased risk of cardiovascular diseases (CVDs), with an 18% higher likelihood of developing CVDs compared to controls. The study, primarily involving Asian patients, found that specific PCA subtypes, such as folliculitis decalvans and lichen planopilaris (LPP), are linked to a pronounced increase in cardiovascular risk. Men with PCA, particularly those with neutrophilic subtypes, may be more susceptible to cardiovascular damage. The findings suggest that chronic inflammatory skin diseases like PCA contribute to endothelial dysfunction and elevated cardiovascular risk, emphasizing the need for further research into the systemic implications of hair disorders.
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