December 2017 in “Elsevier eBooks” Vitamin D receptor is crucial for hair growth, not vitamin D itself.
January 2024 in “Biomedical journal of scientific & technical research” This study explores the critical role vitamins A, B7, C, D, and E play in regulating hair growth and protecting against damage, emphasizing their potential in addressing hair issues linked to nutritional deficiencies.
December 2009 in “Expert review of dermatology” This article reviews evidence suggesting that vitamin D and its metabolite may help protect against nonmelanoma skin cancer, but reports no new empirical findings.
March 2023 in “Photodiagnosis and Photodynamic Therapy” This study found that vitamin D levels were lower in alopecia areata patients, with trichoscopic features like broken hairs and black dots more prevalent in cases with vitamin D deficiency.
This review examines the role of vitamin D and its receptor in skin functions, exploring mechanisms regulating proliferation, differentiation, immunity, and tumor suppression, without reporting new research findings.
January 2012 in “Human health handbooks” This review examines the various functions of vitamin D and its receptor in regulating skin processes, highlighting their role in cell differentiation, immunity, and tumor suppression, but reports no new clinical results.
May 2020 in “Current developments in nutrition” This study suggests that retinoic acid synthesis and signaling may play a role in maintaining refractory telogen, potentially inhibiting the hair cycle in mice fed varying levels of vitamin A.
February 2022 in “Scientia Pharmaceutica” This study validated that six out of seven tested topical formulations for alopecia are compatible for 6-month use, suggesting they may be practical for compounding pharmacies.
September 2010 in “대한화장품학회지(J. Soc. Cosmet. Scientists Korea)” This study developed and validated a method to analyze active ingredients in hair nourisher products, which was successfully applied to products from the market.
9 citations
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May 2002 in “PubMed” This study demonstrated that mice lacking skin-specific RXRalpha expression developed hair follicle degeneration and alopecia, indicating the importance of RXRalpha/VDR heterodimers in maintaining hair follicle homeostasis.
15 citations
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June 2016 in “Computers in Biology and Medicine” This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.
This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.
June 2026 in “International Journal of Homoeopathic Sciences” In this case report, a 22-year-old female with recurrent alopecia totalis experienced progressive hair regrowth and scalp health normalization over eight months following individualized homeopathic treatment and nutritional support.
September 2024 in “Polish Journal of Public Health” The researchers reported finding 53 therapeutic and skincare products for hirsutism and hypertrichosis in Polish pharmacies and drugstores, identifying dienogest and cyproterone acetate as common active ingredients for hirsutism. They noted promising new treatments include eflornithine, acyclovir, licorice, and vitamin D.
November 2022 in “Journal of the Endocrine Society” In this case study, a woman with high 25(OH)D levels and persistent symptoms showed decreased parathormone after transdermal estrogen therapy, highlighting the importance of assessing both parathormone and estrogen levels in similar patients.
23 citations
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June 1993 in “PubMed” This study found that a vitamin B-group and L-cystine combination therapy improved hair quality and growth in women with diffuse effluvia, with one formulation showing greater efficacy than another and both performing better than placebo.
This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.
October 2023 in “International Journal of Pharmaceutics” This study found that ethosome-loaded minoxidil and tocopherol acetate improved hair regeneration and regulated the microenvironment around hair follicles better than commercial minoxidil in androgenic alopecia model mice, showing promise as a treatment strategy.
December 2021 in “Journal of Applied Biological Chemistry” This study observed that toothpaste and its active constituents promoted hair growth in mice, suggesting their potential for hair growth applications.
June 2024 in “The Journal of Nutritional Biochemistry” This study found that 1,25-dihydroxyvitamin D3 promotes hair growth and regeneration in mice by prolonging the anagen phase and counteracting DHT's inhibitory effects, suggesting its potential therapeutic role for androgenetic alopecia.
January 2019 in “Springer eBooks” PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.
55 citations
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May 1985 in “Archives of Dermatology” This study found that alopecia in four children was linked to severe calcitriol-resistant rickets, suggesting this condition should be considered among inherited hair growth disorders.
October 2023 in “Apollo medicine” This review highlights that the epidermis acts as an endocrine organ, synthesizing and responding to hormones such as corticosteroids and Vitamin D, impacting processes like hair growth and immune response, and participating in regulating endocrine balance.
11 citations
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May 1985 in “Archives of Dermatology” This study found that calcitriol-resistant rickets is associated with alopecia in children and should be considered in the differential diagnosis of hair loss.
January 2006 in “Actualidad laboral” In this study, vitamin D3 analogs significantly stimulated hair growth in nude mice with congenital alopecia, whereas the natural form of vitamin D3 did not have the same effect.
400 citations
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January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.
83 citations
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August 2020 in “Resources” This review highlights the potential of marine macroalgae as a largely untapped resource for developing new active ingredients in the cosmetic industry, emphasizing their role in supporting circular economy models by utilizing waste from other industrial sectors.
29 citations
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December 2011 in “British Journal of Dermatology” The researchers reported that a novel leave-on treatment containing caffeine, niacinamide, panthenol, dimethicone, and an acrylate polymer significantly increased the diameter and improved the mechanical properties of scalp hair fibers, suggesting it may help mitigate thinning hair.
6 citations
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May 2011 in “Pharmacognosy Journal” This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.
27 citations
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September 2013 in “The FASEB Journal” This study reports that the loss of the protein Memo in mice leads to a reduced lifespan and suggests that Memo is a key regulator of FGFR signaling and vitamin D production.