TLDR Toothpaste containing α-tocopherol acetate, l-menthol, and stevioside can promote hair growth in mice.
The research studied the impact of toothpaste on hair growth in C57BL/6 mice. It was found that applying 10%, 20%, and 50% toothpaste significantly promoted hair growth, with the 20% and 50% groups showing effects earlier than the control group and the group using 3% minoxidil. The study identified a mixture of α-tocopherol acetate, l-menthol, and stevioside as the active components in toothpaste that promote hair growth. However, other components used in toothpaste formulation did not show hair growth effects. Therefore, the hair growth effect of toothpaste is attributed to the mixture of α-tocopherol acetate, l-menthol, and stevioside.
Cited in this study
7 / 7 results
28 citations
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March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
40 citations
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February 2019 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
22 citations
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February 2017 in “Clinical and Experimental Dermatology” Icariin helps mouse hair grow by boosting a growth factor in skin cells.
30 citations
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December 2014 in “Toxicological Research” Peppermint oil can effectively promote hair growth without being toxic.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
300 citations
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October 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
321 citations
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January 2010 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.