TLDR Vitamin D3 analogs can stimulate hair growth in mice with alopecia.
The study investigated the role of vitamin D3 and its synthetic analogs in stimulating hair growth in nude mice with congenital alopecia. It was found that while the active form of vitamin D3, 1,25 dihydroxyvitamin D3, did not affect hair growth, its synthetic analogs significantly stimulated hair growth in these mice. The hair growth was cyclical and accompanied by the formation of normal hair follicles and increased expression of specific keratins. The results suggested that vitamin D3 analogs could initiate hair follicle cycling and stimulate hair growth by acting on keratinocytes.
40 citations
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October 2002 in “Endocrinology” Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
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April 2007 in “Kidney international” Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
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January 2011 in “Turkish Journal of Medical Sciences” Low iron levels are a significant risk factor for hair loss, while high vitamin D levels might be a response to hair loss, not a cause.
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October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
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November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
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November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.