The Skin and Vitamin D

    January 2012 in “ Human health handbooks ”
    Daniel D. Bikle
    Studysummary This review examines the various functions of vitamin D and its receptor in regulating skin processes, highlighting their role in cell differentiation, immunity, and tumor suppression, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 23

    1. Quantification of the Vitamin D Receptor-Coregulator Interaction Biochemistry · 2009
    2. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice Endocrine reviews · 2008
    3. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    4. The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008
    5. Vitamin D Receptor Is Essential For Normal Keratinocyte Stem Cell Function Proceedings of the National Academy of Sciences · 2007
    6. Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse Journal of cellular physiology · 2006
    7. Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes Endocrinology · 2005
    8. FOXE1, A New Transcriptional Target Of GLI2, Is Expressed In Human Epidermis And Basal Cell Carcinoma Journal of Investigative Dermatology · 2004
    9. Physical And Functional Interaction Between The Vitamin D Receptor And Hairless Corepressor, Two Proteins Required For Hair Cycling Journal of Biological Chemistry · 2003
    10. K6irs1, K6irs2, K6irs3, And K6irs4 Represent The Inner-Root-Sheath-Specific Type II Epithelial Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2003
    11. Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    12. Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    13. Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia Endocrinology · 2001
    14. Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    15. Extrarenal Expression of 25-Hydroxyvitamin D3-1α-Hydroxylase The Journal of Clinical Endocrinology & Metabolism · 2001
    16. Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice Endocrinology · 2000
    17. Induction of Basal Cell Carcinomas and Trichoepitheliomas in Mice Overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000
    18. The Role of the Hairless (Hr) Gene in the Regulation of Hair Follicle Catagen Transformation American Journal Of Pathology · 1999
    19. Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice Endocrinology · 1998
    20. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    21. Analysis of the Relation Between Alopecia and Resistance to 1,25-Dihydroxyvitamin D Clinical Endocrinology · 1986
    22. Calcitriol-Resistant Rickets With Alopecia Archives of Dermatology · 1985
    23. Topographical and Developmental Studies on Target Sites of 1,25 (OH)₂ Vitamin D₃ in Skin Cell & tissue research/Cell and tissue research · 1984