4 citations
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September 2006 in “Prescriber” This review discusses acne pathogenesis and management, outlining key stages of the condition and summarizing various treatment options, but it reports no new clinical findings.
August 2022 in “Journal of Contemporary Medical Practice” This review discusses the possible roles of skin and intestinal microbiota in acne pathogenesis and covers related research on traditional Chinese medicine treatments, without reporting new clinical results.
research Acne
4 citations
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May 1978 in “JAMA” This article reviews the pathogenesis and prevalence of acne, emphasizing that neglecting treatment can lead to permanent scarring and emotional trauma, but presents no new findings.
57 citations
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August 2018 in “British Journal of Dermatology” This review discusses the pathogenesis and treatment of acne in transgender men on testosterone therapy and reports no new clinical results, emphasizing the need for tailored guidelines.
1 citations
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March 2023 in “International Journal of Health and Pharmaceutical Medicine” This review summarizes the link between acne pathogenesis and skin barrier dysfunction, noting that more severe acne correlates with greater skin barrier damage, but reports no new clinical results.
September 2021 in “CRC Press eBooks” This article discusses the characteristics and pathogenesis of acne keloidalis nuchae among men with coarse curly hair, reviewing its association with factors like chronic inflammation and potential roles for metabolic syndrome and infection. It reports no new results.
24 citations
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June 2008 in “Journal of Cutaneous Pathology” This review discusses varying views on the pathogenesis of hidradenitis suppurativa and the challenges in achieving a consensus, emphasizing the need for further research rather than providing new findings.
5 citations
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July 2008 in “Journal of Cutaneous Pathology” This review discusses various perspectives on the pathogenesis, classification, and contributing factors of hidradenitis suppurativa and reports no new experimental results; the authors call for further studies to advance understanding and treatment.
2 citations
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July 2022 in “Cutis” This review discusses the role of the mTORC1 pathway in acne pathogenesis in relation to diet and reports no new results.
1 citations
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November 2011 in “Open access journal of contraception” This article reviews the role of androgens and oral contraceptives in acne pathogenesis and management but presents no new clinical results.
June 2023 in “World Journal of Biology Pharmacy and Health Sciences” This review outlines the complex factors involved in acne pathogenesis—including hormonal, genetic, and environmental influences—and describes current comprehensive management strategies, emphasizing both topical and systemic therapies, while also highlighting emerging treatment options and the significant psychological impact of acne.
November 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review discusses the role of androgens and estrogens in acne pathogenesis and the potential use of oral contraceptives containing ethinyl estradiol and progestins to manage acne, but reports no new results.
April 2019 in “Journal of the Dermatology Nurses’ Association” This article reviews the characteristics, pathogenesis, and treatment strategies for folliculitis decalvans, emphasizing the importance of early recognition and treatment to mitigate hair loss, but reports no new clinical results.
May 2024 in “Aktualʹnì problemi sučasnoï medicini: Vìsnik Ukraïnsʹkoï medičnoï stomatologìčnoï akademì” This review discusses the multifactorial pathogenesis of acne and current treatment strategies including the use of isotretinoin and spironolactone, but reports no new clinical results.
10 citations
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January 2020 in “Advances in Dermatology and Allergology” This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.
21 citations
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July 2014 in “Clinics in Dermatology” This review examines the role of hormones in acne pathogenesis, the use of hormonal therapies for treatment, and the importance of contraceptive counseling during isotretinoin therapy, but reports no new clinical results.
93 citations
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January 2016 in “British Journal of Dermatology” This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.
74 citations
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October 2015 in “Experimental Dermatology” This study found that mTOR gene expression was significantly increased and S6K1 activation was observed in skin samples from acne patients compared to healthy controls, suggesting mTORC1's involvement in acne pathogenesis.
7 citations
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March 2018 in “Experimental Dermatology” This study found no evidence of increased keratinocyte proliferation in acne vulgaris, suggesting that other mechanisms may be responsible for hyperkeratinization in acne pathogenesis.
1 citations
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November 2015 in “European medical journal” This article reviews the complex role of various biological, genetic, and environmental factors in acne pathogenesis and notes no new clinical results.
August 2025 in “Scientific Reports” This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.
July 2025 in “Annals of Human Genetics” This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this hospital-based study, researchers found that serum ferritin levels were significantly lower in individuals with acne compared to healthy controls, suggesting a possible link between iron deficiency and acne pathogenesis.
April 2024 in “Molecules/Molecules online/Molecules annual” This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.
March 2022 in “Osmangazi tıp dergisi” This study found that both oxidant and antioxidant levels were elevated in acne patients, suggesting that oxidative stress may be linked to acne pathogenesis but its causal role remains unclear.
January 2008 in “Padua Research Archive (University of Padua)” This study observed that hereditary factors were associated with acne duration but not severity, and found a potential role of CYP450 1A1 polymorphisms in acne pathogenesis.
2 citations
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January 2018 in “Elsevier eBooks” This review discusses the complex mechanisms behind acne vulgaris and suggests that dietary modification, along with pro- and prebiotics, may influence its pathogenesis by addressing stress-induced skin inflammation.
October 2020 in “Benha Journal of Applied Sciences” This study observed that patients with acne vulgaris had significantly lower serum vaspin levels and higher insulin resistance, suggesting a potential role of vaspin in the disease's pathogenesis.
October 2024 in “Tikrit Journal of Pure Science” This study found that the Geh gene responsible for lipase enzyme production was highly expressed in Staphylococcus aureus isolates from acne patients, implicating this enzyme in the infection's pathogenesis.
June 2023 in “Lithuanian University of Health Sciences” This study found that acne tarda is prevalent, particularly among women and individuals with darker skin, with hormonal imbalances and endocrine disorders like PCOS commonly associated with its pathogenesis.