September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in hidradenitis suppurativa, the proteins SERPINB3/B4 and S100A7/A8/A9 were significantly overexpressed in lesional skin compared to nonlesional skin, suggesting new pathways in the disease's pathogenesis.
65 citations
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February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.
October 2021 in “Turkderm” This study found that women with post-adolescent acne experience marked menstrual irregularities, polycystic ovaries, androgenetic alopecia, hirsutism, and metabolic syndrome, but insulin resistance and dyslipidemia may not significantly contribute to their acne's pathogenesis.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.
16 citations
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July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
66 citations
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March 2009 in “British journal of surgery” This review discusses hidradenitis suppurativa's pathogenesis, including its inflammatory nature and the role of smoking as a triggering factor, but reports no new clinical results.
47 citations
,
March 2022 in “Frontiers in cellular and infection microbiology” This review discusses the role of the skin microbiome in the pathogenesis of various skin disorders, such as atopic dermatitis and psoriasis, and reports no new clinical findings; it emphasizes potential therapeutic implications.
October 2024 in “Our Dermatology Online” This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.
27 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
3 citations
,
March 2022 in “Chinese Journal of Plastic and Reconstructive Surgery” This review discusses the potential role of androgen-related disorders in keloid pathogenesis and highlights the need for systemic treatments targeting sex hormones, but reports no new clinical results.
August 2023 in “Journal of Knowledge Learning and Science Technology ISSN 2959-6386 (online)” This review discusses the use of single-cell RNA sequencing and spatial transcriptomics to enhance understanding of the pathogenesis and targeted therapies for chronic inflammatory skin conditions, highlighting technology advancements and the need for cost reduction and standardization.
60 citations
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October 2014 in “Journal of the American Academy of Dermatology” This review examines the definition, etiology, pathogenesis, and clinical features of polycystic ovary syndrome but reports no new clinical findings.
97 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.
76 citations
,
October 2016 in “Clinics in dermatology” This review discusses the hormonal and genetic factors influencing acne development, emphasizing the role of androgens and insulin signaling but reports no new clinical results.
43 citations
,
September 2012 in “International Journal of Dermatology” This review describes a practical approach for dermatologists to manage adult female acne using hormonal therapies and highlights the importance of identifying possible underlying endocrine disorders like PCOS, but it does not report new findings.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
14 citations
,
June 2016 in “Seminars in Cutaneous Medicine and Surgery” This review examines hormonal therapies for acne in females, noting their effectiveness and encouraging further study and use to reduce antibiotic reliance, but it reports no new results.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
January 2018 in “Springer eBooks” The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.
January 2005 in “Experimental Dermatology” This abstract reviews recent findings on genetic factors in acne, highlighting the potential of genetic studies to advance understanding of its pathogenesis, but reports no new clinical results.
January 2019 in “Advances in Environmental Biology” This article discusses the structure and function of sebaceous glands and their role in skin moisture but reports no new research findings.
15 citations
,
December 2021 in “Pharmaceutics” This systematic review identified robust biomarkers associated with hidradenitis suppurativa and confirmed potential drugs for repurposing, highlighting key pathogenetic pathways and their links to comorbid disorders.
3 citations
,
August 2024 in “Frontiers in Immunology” This source reports that understanding how skin cells and immune cells interact may lead to better treatment options for inflammatory skin diseases like psoriasis and atopic dermatitis, emphasizing the role of epithelial-immune microenvironments in disease pathogenesis.
April 2023 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This collection presents a photogallery on the follicular occlusion syndrome, uniting diseases like hidradenitis suppurativa under shared pathogenesis, but reports no new clinical results.
This article discusses the inflammation process in dissecting cellulitis and folliculitis keloidalis, noting the role of follicular rupture and hair fragments while reporting no new results; the authors highlight differences in bacterial presence and pathogenesis understanding.
September 2005 in “Clinics in Plastic Surgery” This article discusses multiple aspects of complex regional pain syndrome, including its diagnosis, pathogenesis, and treatment, but reports no new scientific findings.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.
71 citations
,
November 2013 in “Clinics in Dermatology” This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.
51 citations
,
September 2015 in “Medical Clinics of North America” This review discusses common skin appendage diseases, including their pathophysiology and treatments, but does not report new results.
22 citations
,
March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.