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This study found that in genetically diabetic mice, supplementation with safflower or evening primrose oil prevented the decrease in certain fatty acids and improved skin conditions, but increased plasma glucose levels.

This review discusses the role of jasmonic acid and its conjugates in enhancing plant stress tolerance and balancing growth and defense mechanisms but provides no new experimental data.

A fatty acid/protein complex in human hair helps protect it from damage.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

This study found that altered amino acid metabolism, specifically involving glutamic and aspartic acids, promotes neurovascular reactivity in rosacea, suggesting a potential metabolic target for treatment.

This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.

This study found that unsaturated fatty acids are more abundant in the cortex of human hair than on its surface, and steryl glycoside-like lipids may help bind the cuticle to the cortex.

In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.

This study found that linoleic acid from Malva verticillata seed extracts may promote hair follicle cell growth and counteract hair loss signaling in a lab setting.

This study found that ferulic acid promotes wound healing by inhibiting β-catenin in keratinocytes and activating Nrf2 to reduce inflammation at the wound edge.

In this study, valproic acid treatment did not significantly affect serum biotinidase enzyme activity in children, but was associated with hair loss in some patients, which resolved with biotin supplementation.

The authors concluded that administering biotin may help prevent alopecia caused by reduced biotinidase activity during valproic acid therapy in rats.

Hair amino acid levels can indicate metabolic disorders.

This study found that vanillic acid from wheat bran promoted dermal papilla cell proliferation, potentially stimulating hair growth by activating the PI3K/Akt and Wnt/β-catenin pathways.

This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.

This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.

This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.

This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.

This case collection reports that 15% azelaic acid gel can be effectively used as a monotherapy to treat mild-to-moderate adult female acne.

This study identified an optimal sulfate-free and silicone-free conditioning shampoo formulation using 1% hyaluronic acid at 800 kDa, 10% acidic sophorolipid, and 1% sodium chloride, which maintains essential conditioning and cleansing properties without compromising on performance.

This study identified two cytochrome P450 enzymes in Avicennia marina leaves that may contribute to the biosynthesis of triterpenoids, potentially responsible for the plant's medicinal properties.

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.

This study found that higher levels of DHA from omega-3 fatty acids delayed inflammation resolution and impaired wound healing quality in both transgenic mice and wild-type mice supplemented with DHA.

This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This review examines the benefits of topical hyaluronic acid in cosmetic applications, noting its ability to penetrate the skin in low-molecular-weight forms and highlighting safety supported by clinical trials.

This study found that purified humic acids from oxidized coal enhance plant growth by modulating oxidative stress and influencing photobiological processes, with improved root growth and enzyme activity linked to antioxidant and pro-oxidant properties.

This study found that glycyrrhetinic acid, derived from licorice, may help alleviate acne symptoms by regulating lipid synthesis and inflammatory responses through multiple pathways, as observed in both in vitro and in vivo settings.