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New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

The new gel improves skin delivery of a drug, potentially reducing dose frequency and side effects.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.

Higher CRBP1 levels are linked to more severe alopecia areata.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Seminal bacteria can lower sperm quality in subfertile men.

Pregnancies in a woman with the Donohue mutation were managed with genetic testing, resulting in three healthy infants.

New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.

Patients with anorexia nervosa did not show a correlation between zinc levels and taste perception or the severity of their condition.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Apoptosis is essential for human skin development and forming a functional epidermis.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

CDP is crucial for lung and hair follicle cell development.