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The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

Sex steroids affect the MafB gene differently in male and female hamsters.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

The research identified genes and pathways important for sheep wool growth and shedding.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Methotrexate side effects vary by race and sex.

Specific genes influence hair and cashmere growth in Laiwu black goats.

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Certain RNA molecules are important for the development of wool follicles in sheep.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

New understanding and treatments for hair loss are improving, but more research is needed.

Certain genetic markers linked to wool quality in Rambouillet sheep were identified, which can guide better breeding choices.

Minoxidil can stop the growth of ovarian cancer cells without harming the heart.

Genomic approach finds new possible treatments for hair loss.