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Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Lespedeza cuneata extract may help treat enlarged prostate.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Sphinganine can reduce hair loss and improve scalp health.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride doesn't affect sleep spindles in men.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Testosterone's muscle-building effects do not require its conversion to DHT.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

DHT stops hair regrowth in mice, similar to human hair loss.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Finasteride helps protect brain in old male rats.