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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

New compounds may soon be tested to treat excessive hair growth in women.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Finasteride helps treat hair loss by blocking enzyme activity.

Current research explores hair growth drugs, while future research aims for personalized treatments.

Hair loss in women is often due to hereditary conditions or stress, and while treatments like minoxidil can help, diagnosis and management require medical guidance.

Too much androgen can cause hair loss; finasteride may help.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Long-term finasteride use doesn't change bone density or metabolism.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Treatment during development affects hormone balance and sexual behavior in male rats.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Higher androgen levels do not cause baldness in men.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.