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5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Finasteride doesn't affect sleep spindles in men.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Licorice extract helps hair growth and may treat hair loss.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

A new compound effectively inhibits human 5α-reductase 1.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.

Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.

Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Finasteride safely lowers DHT levels without affecting testosterone.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.