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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Rice bran extract might help prevent hair loss.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Some herbs show promise as antiandrogenic agents.

Compounds from the plant Mammea siamensis may help treat hair loss.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.