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DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Finasteride helps manage male hair loss, but realistic expectations and support are crucial.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Gene differences may affect baldness treatment response in Korean men.

Finasteride improves hair loss in women with hyperandrogenism.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride effectively treats male hair loss, improving growth and density.