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Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Finasteride potentially treats hair loss by reducing DHT production.

Dutasteride may help shrink prostate cancer tumors.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

Solanum nigrum may help treat hair loss.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Finasteride for hair loss increases risk of sexual dysfunction in young men.

Green tea extract may help reduce excessive hair growth.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Pomegranate peel compounds may help treat hair loss.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.