Sexual Dysfunction After 5-Alpha Reductase Inhibitor Use: Insights from the Reduce Study Group Database
April 2018
in “
The Journal of Urology
”
TLDR Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.
The study analyzed data from 7909 men over four years to assess the impact of dutasteride, a 5-alpha reductase inhibitor used to treat benign prostatic hypertrophy and androgenic alopecia, on sexual function. The results showed that men on dutasteride had comparable baseline and decreased Problem Assessment Scale of the Sexual Function Index (PAS-SFI) scores at 1, 2, 3, and 4 years following drug exposure. The decline in sexual function associated with dutasteride remained stable beyond the first year and was not influenced by age or prostate size.
