July 2024 in “Fitoterapia” Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
75 citations,
October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
The conclusion is that hair supplement ingredients may be unsafe and should be disclosed and proven safe before use.
87 citations,
March 2005 in “Journal of Dermatological Science” Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
4 citations,
August 2021 in “Annals of Translational Medicine” Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
5 citations,
November 2003 in “Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic” The exact causes of baldness are not fully understood, limiting treatment options.
12 citations,
January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
21 citations,
November 2017 in “Archives of Dermatological Research” Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
13 citations,
June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
153 citations,
March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
12 citations,
June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
59 citations,
November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
23 citations,
January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
1 citations,
January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
20 citations,
November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
11 citations,
February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
6 citations,
January 2021 in “International Journal of Molecular Sciences” Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
February 2024 in “International journal of biology, pharmacy and allied sciences” Plant-based treatments can effectively and safely treat hair loss.
April 2016 in “Annals of laboratory medicine” The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
54 citations,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
6 citations,
June 2010 in “Fertility and Sterility” Finasteride helps induce ovulation in nonresponder PCOS women.
March 2018 in “Nepal journal of dermatology, venereology & leprology” Hair loss linked to prostate enlargement; stress and family history important factors.
54 citations,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
The new treatment regimen was effective in promoting significant hair growth in all 15 male patients with androgenic alopecia.
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.