Search

everythinglearnresearchcommunity

for

Search:↓

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Dutasteride may help shrink prostate cancer tumors.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Plumbago zeylanica extract helps hair growth and reduces a hair loss-related enzyme.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Rice bran extract might help prevent hair loss.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Finasteride doesn't affect ovulation in normal women.

DA-9401 helps protect rat testis from finasteride damage.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.