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research OBECNY I PRZYSZŁY WPŁYW POSTĘPU TECHNOLOGICZNEGO I WIRTUALNEGO PLANOWANIA 3D NA CHIRURGIĘ ORTOGNATYCZNĄ I ZABIEGÓW REKONSTRUKCJI: POPRAWA WYDAJNOŚCI, KOORDYNACJI I PRECYZJI
This study highlights the benefits of virtual surgical planning in orthognathic and facial trauma surgeries, noting its ability to enhance understanding of complex 3D anatomical relationships, reduce operation time, and integrate multidisciplinary approaches, including robotic assistance for real-time adjustments and customized implants.
research An Overview of Recent Progress in Engineering Three-Dimensional Scaffolds for Cultured Meat Production
This overview outlines the latest advancements and challenges in developing three-dimensional scaffolds for biomanufacturing cultured meat, focusing on organizing muscle stem cells to better mimic the structure of traditional meat. Results are not reported in the abstract.
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
This study found that generating pluripotent stem cell-derived skin organoids in a 3D bioprinted hydrogel device improved keratinocyte differentiation and hair follicle formation while reducing necrosis.
research Design and initial characterization of fabricated composite scaffold dHPCTM-HPE (decellularized human placental connective tissue matrix - human placental extract)
This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.
research Tissue engineering ECM-enriched controllable vascularized human microtissue for hair regenerative medicine using a biomimetic developmental approach
This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.
research 3D multicellular micropatterning biomaterials for hair regeneration and vascularization
This study developed 3D micropatterns with magnesium silicate nanospheres that mimic vessels and hair follicles for potential use in skin regeneration by reconstructing vasculature and promoting hair growth.
research 655 In vitro cultivation of dermal-epidermal composites in a single medium supports human hair follicle neogenesis in xenografts
A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.
research 1415 Induction of human hair growth using vascularized 3D hair follicle constructs
This study demonstrated that prevascularized human skin constructs containing engineered hair follicles can successfully induce human hair growth when grafted onto mice by promoting blood supply to the grafted skin.
research Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration
This review discusses the advancements and challenges in skin bioprinting techniques and applications, including hair follicles and pigmentation, while addressing the need for improvements in vascularization, safety, and clinical translation, according to the authors.
research Towards developing an organotypic model for the preclinical study and manipulation of human hair matrix-dermal papilla interactions
This study developed a new human hair research model combining 3D spheroid dermal papilla fibroblasts with plucked anagen hair shafts, potentially improving the evaluation of hair follicle differentiation.
research Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis
This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.
research Is Three-Dimensional Virtual Planning in Cranial Reconstruction for Advanced Cutaneous Squamous Cell Carcinoma of the Skull a Feasible Option?
In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.
research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling
This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.
research 3D printing of microneedle arrays for hair regeneration in a controllable region
This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.
research 591 A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
This study developed a 3D skin model with immune and endothelial cells, which may enhance understanding of skin biology and diseases due to its closer approximation to native skin.
research Various Three-Dimensional Culture Methods and Cell Types for Exosome Production
research [Effects of immune responses mediated by topological structures of three-dimensional bioprinted scaffolds on hair follicle cycle in mice].
This study investigated how different 3D bioprinted scaffold structures affect immune responses and hair growth in mice, finding that moderate immune response induced by certain structures stimulates hair growth, while excessive immune response can hinder hair follicle development.
research Poor Capability of 3D-Cultured Adipose-Derived Stem Cells to Induce Hair Follicles in Contrast to 3D-Cultured Dermal Papilla Cells
This article discusses the factors contributing to acne and reports no new findings, focusing on the role of sebaceous lipids and associated processes.
research Electrospun Fibrous Sponge via Short Fiber for Mimicking 3D ECM
This research observed that 3D electrospun micro/nanofibrous sponges, without using chemical crosslinking agents, supported enhanced cell growth, vascularization, and skin regeneration in diabetic rats compared to 2D fiber membranes, making them promising for 3D tissue regeneration.
research Impact of substrate stiffness on dermal papilla aggregates in microgels
This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.
research Monte Carlo simulation‐guided design for size‐tuned tumor spheroid formation in 3D printed microwells
This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.
research Integrating zinc/silicon dual ions with 3D-printed GelMA hydrogel promotes in situ hair follicle regeneration
This study found that a bioprinted hydrogel scaffold with zinc and silicon ions significantly activated hair follicle stem cells and enhanced blood vessel formation, promoting hair growth in mouse wound models.
research Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells
This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.
research Complex Scalp Reconstruction with Super Thin DIEP Free Flap
In this case report, successful scalp reconstruction was achieved for a 67-year-old man using a super thin DIEP flap, a technique adapted from breast reconstruction that shows promise in head and neck surgeries for improving wound contour and skin coverage.
research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth
This study found that altering cell culture conditions to form three-dimensional papilla spheroids can restore the ability of human dermal papilla cells to induce hair growth in adult skin.
research “How can stem cells improve the function of skin grafts”
This abstract introduces 3D bioprinted skin grafts as a promising alternative to traditional skin grafts, emphasizing how using stem cells in the bioink can enhance vascularization and hair follicle regeneration, potentially improving graft integration and function without the donor site risks.
research Skin 3D Bioprinting. Applications in Cosmetology
This review discusses the potential of bioprinting technology in cosmetology, particularly for improving skin functions like pigmentation restoration and hair follicle development, but reports no new clinical findings.
research 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla
This study used single-cell and spatial transcriptomic profiling to identify specific molecular markers in human follicular dermal papilla cells, enhancing understanding of their role in hair follicle development.