Electrospun Fibrous Sponge via Short Fiber for Mimicking 3D Extracellular Matrix
March 2021
in “
Research Square (Research Square)
”
electrospun micro/nanofibrous sponge extracellular matrix ECM cell adhesion cell growth electrospinning thermal crosslinking Human Umbilical Vein Endothelial Cells HUVECs Vascular Endothelial Growth Factor VEGF vascularization chronic diabetes wounds full-thickness skin defects wound healing hair follicle regeneration angiogenesis collagen secretion 3D tissue regeneration
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This research observed that 3D electrospun micro/nanofibrous sponges, without using chemical crosslinking agents, supported enhanced cell growth, vascularization, and skin regeneration in diabetic rats compared to 2D fiber membranes, making them promising for 3D tissue regeneration.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on researchsquare.com →