Bio-Based Electrospun Fibers for Wound Healing

September 2020 in “ Journal of Functional Biomaterials ”

Bahareh Azimi, Homa Maleki, Lorenzo Zavagna, Jose Gustavo De la Ossa, Stefano Linari, Andrea Lazzeri, Serena Danti

Studysummary This review discusses bio-based polymers, highlighting their potential in wound healing applications, but reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The review discussed the potential of bio-based electrospun fibers for wound healing, highlighting their biocompatibility, biodegradability, and bioactivity. These fibers, created through electrospinning, mimic the extracellular matrix, promoting tissue regeneration and healing. Various biopolymers like cellulose, chitosan, and polylactides were used, offering tunable properties for advanced wound dressings. The fibers provided a moist environment, reduced bacterial infection, and allowed for bioactive molecule incorporation, enhancing healing. Studies showed improved wound closure and healing outcomes, with specific blends offering tailored properties for different medical applications. Despite promising research, commercial availability faced challenges due to production and regulatory hurdles.

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