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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Minoxidil dissolves better in propylene glycol + water than in supercritical CO2.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.