This study found that lateral root formation in plants in response to L. bicolor volatiles involves complex signaling processes, potentially including unknown proteins, CRKs, and ABA pathways.
7 citations
,
April 2022 in “Journal of pharmaceutical and biomedical analysis” This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.
March 2020 in “Endocrinology research and practice.” In this study, treating prolactinoma with cabergoline normalized prolactin levels and affected some androgen-related parameters, but did not significantly improve hirsutism in affected women.
78 citations
,
November 2014 in “Functional Ecology” This study found that wolves in heavily hunted areas of Canada's tundra–taiga exhibited higher levels of stress and reproductive hormones, indicating social instability and increased reproductive effort due to human-caused mortality.
30 citations
,
July 2023 in “Clinical Chemistry and Laboratory Medicine (CCLM)” In this study, researchers developed an LC-MS/MS method to accurately quantify cortisone and cortisol levels in human scalp hair, finding that concentrations decrease predictably along the hair shaft, which could assist in identifying abnormal glucocorticoid exposure.
7 citations
,
November 2022 in “Toxics” This study developed and validated a highly sensitive LC-MS/MS method for detecting multiple steroid hormones in urine and serum/plasma, demonstrating its potential for use in large-scale biomonitoring studies.
26 citations
,
July 2012 in “Endocrine Connections” This study found that mitotane causes specific changes in cortisol metabolism, including increased excretion of certain metabolites, which may influence cortisol bioavailability without hindering early detection of adrenocortical carcinoma recurrence.
September 2025 in “JCEM Case Reports” In this case report, a 46-year-old woman initially diagnosed with 21-hydroxylase deficiency congenital adrenal hyperplasia was later identified as having 3β-HSD2 deficiency after further investigation, highlighting the need for awareness of rarer CAH forms to prevent delayed diagnosis and insufficient treatment.
46 citations
,
September 2011 in “Journal of Endocrinology” This study suggests that 5α-reduced glucocorticoids may have anti-inflammatory potential and could serve as biomarkers for liver inflammation in metabolic disease, with implications for drug development.
13 citations
,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
59 citations
,
November 2018 in “Psychoneuroendocrinology” This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.
22 citations
,
February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews the evidence regarding the role of sex hormones in occult hyperadrenocorticism and reports no new findings, highlighting the unproven nature of their involvement.
54 citations
,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” This review discusses the controversial non-inflammatory alopecia known as alopecia X, highlighting its unknown etiology and the variable effectiveness of various proposed treatments, but reports no new results.
54 citations
,
August 2005 in “Alcohol” This study found that acute finasteride treatment decreased ethanol intake in male C57BL/6J mice, whereas chronic treatment showed diminished effects, implying compensatory changes in neurosteroid modulation.
51 citations
,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.
July 2015 in “Cambridge University Press eBooks” The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
4 citations
,
September 2010 in “Medical Hypotheses”
2 citations
,
September 2009 in “Hormone Molecular Biology and Clinical Investigation” This study found that low-dose finasteride treatment in men with premature androgenetic alopecia decreased levels of 5α-reduced steroids, which may be linked to increased depression symptoms.
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This case study reported hyperandrogenism in non-obese triplet sisters with one sister's hyperthyroidism masking its clinical and biochemical signs until treatment increased her androgen levels and hirsutism.
1 citations
,
May 2018 in “Clinical chemistry” This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.
71 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews the reported sexual and psychological side effects of 5-alpha reductase inhibitors for benign prostatic hyperplasia, emphasizing the need for further clinical studies.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
305 citations
,
February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
49 citations
,
January 2010 in “International Journal of Pediatric Endocrinology” This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.
45 citations
,
January 2006 in “Endocrine journal” To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.
41 citations
,
March 2007 in “Steroids” This article reviews recent advances in the synthesis of oxasteroids and reports no new experimental results.
20 citations
,
October 2017 in “Clinical Endocrinology” This article reviews existing knowledge on postmenopausal hyperandrogenism and highlights diagnostic challenges, reporting no new clinical results.
11 citations
,
August 2019 in “The Journal of Sexual Medicine” This study found that women with nonclassic congenital adrenal hyperplasia (NC-CAH) reported lower sexual function and higher sexual distress compared to those with classic CAH (C-CAH), particularly among those showing signs of androgen excess.
8 citations
,
January 1987 in “Gynecological Endocrinology” This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.