research Vitamin D-Dependent Rickets Type II with Alopecia: A Rare Case Report
A 4-year-old boy with a rare type of rickets and hair loss improved in bone health but not hair growth after vitamin D and calcium treatment.
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research Are Nutraceuticals Effective in Covid-19 and Post-Covid Prevention and Treatment?
Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.
research The Role of Micronutrients in Young Men Presenting with Hair Loss
Many young men with hair loss have low levels of vitamin D and B12.
research Metallothionein Expression During Wool Follicle Development in Fetal Sheep
Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
research Behavioral Characterization of Vitamin D Receptor Knockout Mice
Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.
research Serum Vitamin D Levels and Alopecia Areata: A Hospital-Based Case-Control Study from North India
People with Alopecia areata often have lower Vitamin D levels, which might affect the severity of their condition.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
research Two Siblings With a Novel Nonsense Mutation, p.R50X, in the Vitamin D Receptor Gene
A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.
research Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review
Low vitamin D levels are linked to hair loss, and vitamin D might help treat it.
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
research Effect of a Transcriptionally Inactive or Absent Vitamin D Receptor on Beta-Cell Function and Glucose Homeostasis in Mice
Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.
research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?
Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.
research C-Reactive Protein as a Novel Biomarker for Vitamin D Deficiency in Alopecia Areata
High CRP levels could indicate vitamin D deficiency in people with alopecia areata.
research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Dissecting the Impact of Chemotherapy on the Human Hair Follicle
Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
research Vitamin D and Calcium Signaling in Epidermal Stem Cells and Their Regeneration
Vitamin D and calcium are important for skin stem cell function and wound healing.
research Role of Nutritional Supplements in Selected Dermatological Disorders: A Review
Some diets and supplements might help with skin disorders, but their effectiveness varies and more research is needed.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone
Cyclosporine A slows down hair loss from chemotherapy in mice, while dexamethasone increases hair loss but speeds up regrowth.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research CXXC5: A Novel Regulator and Coordinator of TGF-β, BMP, and Wnt Signaling
CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
research Prevention and Treatment of Chemotherapy-Induced Alopecia
Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
research Vitamin D and the Skin: A Review for Dermatologists
Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
research Impact of a Topical Lotion, CG428, on Permanent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Pilot Randomized Double-Blind Controlled Clinical Trial (VOLUME RCT)
The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.
research A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases
The new topical botanical formulation significantly regrew hair in all five patients without side effects.
research In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration
New methods to test hair growth treatments have been developed.