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    Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study

    January 2020 in “ Experimental Dermatology ”
    Tee Wei Siah, Hongwei Guo, Thomas G. Chu … Kevin J. McElwee
    Studysummary This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.
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    Research cited in this study 29

    1. Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels Journal of The American Academy of Dermatology · 2018
    2. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    3. Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2018
    4. Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia Aesthetic Plastic Surgery · 2017
    5. A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification Skin appendage disorders · 2017
    6. Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature Skin appendage disorders · 2017
    7. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    8. Identification of Key Genes Induced by Platelet-Rich Plasma in Human Dermal Papilla Cells Using Bioinformatics Methods Molecular Medicine Reports · 2016
    9. Platelet-Rich Plasma in Androgenic Alopecia: Indications, Technique, and Potential Benefits Journal of Oral and Maxillofacial Surgery · 2016
    10. Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia Dermatologic Surgery · 2016
    11. Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss American Journal of Clinical Dermatology · 2016
    12. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    13. Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology Journal of Cosmetic Dermatology · 2015
    14. Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy Indian Journal of Dermatology · 2015
    15. Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias International Journal of Trichology · 2015
    16. Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience Indian Journal of Plastic Surgery · 2015
    17. Commentary on Platelet-Rich Plasma for Androgenetic Alopecia Dermatologic Surgery · 2014
    18. The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation BioMed Research International · 2014
    19. Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool Journal of Cutaneous and Aesthetic Surgery · 2014
    20. Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period Journal of Cutaneous and Aesthetic Surgery · 2014
    21. A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata British Journal of Dermatology · 2013
    22. Platelet-Rich Plasma Injection Is Effective and Safe for the Treatment of Alopecia European Journal of Plastic Surgery · 2013
    23. The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study Journal of The European Academy of Dermatology and Venereology · 2012
    24. Letter: Platelet-Rich Plasma for Treating Male Pattern Baldness Dermatologic Surgery · 2012
    25. Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study Journal of Dermatology · 2012
    26. Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012
    27. Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles Journal of The American Academy of Dermatology · 2008
    28. Promoted Growth of Murine Hair Follicles Through Controlled Release of Vascular Endothelial Growth Factor Biomaterials · 2002
    29. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001