Overview of Treatment Methods for Hormonal Hair Loss

April 2024 in “ Tạp chí Y học Thảm hoạ và Bỏng ”

Ngọc Tuấn Nguyễn

androgenetic alopecia AGA hair loss medical treatment surgical treatment light therapy nutritional approaches effectiveness side effects treatment adherence cost

TLDR Choosing the right treatment for hair loss is complex and depends on effectiveness, side effects, practicality, and cost.

The article reviews treatment options for androgenetic alopecia (AGA), including medical, surgical, light therapy, and nutritional interventions. It evaluates the efficacy, side effects, adherence practicality, and cost of these treatments to guide physicians in selecting the most suitable and ethical regimen for patients.

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Research cited in this study

37 / 37 results

research Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients

39 citations, February 2021 in “Journal of The American Academy of Dermatology”

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.

Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment

research Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment

24 citations, September 2020 in “Dermatology and therapy”

Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.

research Microneedling in Androgenetic Alopecia: Comparing Two Different Depths of Microneedles

10 citations, September 2020 in “Journal of Cosmetic Dermatology”

Deeper microneedling boosts hair growth, with 0.6mm needles and minoxidil being most effective.

research Microneedling: A Novel Therapeutic Approach for Androgenetic Alopecia, A Review of Literature

13 citations, September 2020 in “Dermatologic Therapy”

Microneedling may help hair loss, but needs more research.

The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review

research The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review

3 citations, August 2020 in “PubMed”

Some natural ingredients like onion juice, rosemary oil, and pumpkin seed oil may help with hair growth and reducing hair loss.

research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety

59 citations, July 2020 in “Journal of The American Academy of Dermatology”

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

research Clascoterone as a Novel Treatment for Androgenetic Alopecia

5 citations, May 2020 in “Clinical and Experimental Dermatology”

Clascoterone may be a promising treatment for hair loss.

At The Crossroads Of Two Alopecias: Androgenetic Alopecia Pattern Of Hair Regrowth In Patients With Alopecia Areata Treated With Oral Janus Kinase Inhibitors

research At The Crossroads Of Two Alopecias: Androgenetic Alopecia Pattern Of Hair Regrowth In Patients With Alopecia Areata Treated With Oral Janus Kinase Inhibitors

4 citations, April 2020 in “JAAD case reports”

JAK inhibitors help hair regrowth but not fully effective for androgenetic alopecia.

Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality

15 citations, April 2020 in “Journal of Dermatological Treatment”

Minoxidil and finasteride work best for hair loss; more research needed.

research Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients

16 citations, March 2020 in “Journal of The American Academy of Dermatology”

Oral bicalutamide is safe and effective for female hair loss.

research Microneedling for Androgenetic Alopecia Not Responding to Conventional Treatment

3 citations, March 2020 in “Our Dermatology Online”

Microneedling can improve hair growth in people not responding to standard treatments.

research A Study on the Efficacy of Microneedling with Minoxidil Solution Versus Microneedling with Hair Multivitamin Solution for the Treatment of Androgenetic Alopecia

2 citations, March 2020 in “International journal of dermatology and clinical research”

Microneedling helps hair growth, with hair multivitamins showing slightly better results than minoxidil.

research A Review of the Treatment of Male Pattern Hair Loss

53 citations, February 2020 in “Expert Opinion on Pharmacotherapy”

Finasteride and minoxidil work best together for hair loss.

research Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review

5 citations, January 2020 in “Skin appendage disorders”

Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.

research Post-Finasteride Syndrome

11 citations, August 2019 in “BMJ”

Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.

research Minoxidil and Its Use in Hair Disorders: A Review

August 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil is a primary treatment for hair loss but its exact working method is unknown.

Exosomes Derived from Human Dermal Papilla Cells Promote Hair Growth in Cultured Human Hair Follicles and Augment the Hair-Inductive Capacity of Cultured Dermal Papilla Spheres

research Exosomes Derived from Human Dermal Papilla Cells Promote Hair Growth in Cultured Human Hair Follicles and Augment the Hair-Inductive Capacity of Cultured Dermal Papilla Spheres

58 citations, March 2019 in “Experimental Dermatology”

Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.

Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil

research Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil

24 citations, January 2019 in “Journal of Cosmetic Dermatology”

Combining platelet-rich plasma, microneedling, and minoxidil improves hair growth.

research The Use of Serenoa Repens (Saw Palmetto) in Hair Care Products

2 citations, January 2019 in “Biomedical Journal of Scientific and Technical Research”

Saw palmetto in hair products might reduce hair loss but can cause side effects.

research Approach to Hair Transplantation in Advanced Grade Baldness by Follicular Unit Extraction: A Retrospective Analysis of 820 Cases

6 citations, January 2019 in “Journal of Cutaneous and Aesthetic Surgery”

Follicular unit extraction is an effective hair transplant method for advanced baldness with high patient satisfaction, but some experienced decreased density over time.

Evaluating the Efficacy of Different Platelet-Rich Plasma Regimens for Management of Androgenetic Alopecia: A Single-Center, Blinded, Randomized Clinical Trial

research Evaluating the Efficacy of Different Platelet-Rich Plasma Regimens for Management of Androgenetic Alopecia: A Single-Center, Blinded, Randomized Clinical Trial

46 citations, May 2018 in “Dermatologic Surgery”

PRP injections effectively treat hair loss, with positive results in both monthly and every three months treatments.

research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells

87 citations, April 2018 in “Biochemical and Biophysical Research Communications”

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

research Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review

41 citations, December 2017 in “Lasers in Medical Science”

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

research Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone

80 citations, December 2017 in “International Journal of Dermatology”

Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.

Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study

research Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study

34 citations, May 2017 in “Lasers in Surgery and Medicine”

Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations, April 2017 in “Journal of The American Academy of Dermatology”

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

research An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

21 citations, January 2017 in “Skin Pharmacology and Physiology”

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

research Mesotherapy with Dutasteride in the Treatment of Androgenetic Alopecia

24 citations, January 2017 in “International Journal of Trichology”

research Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review

32 citations, July 2016 in “PubMed”

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

research Guidelines on the Use of Finasteride in Androgenetic Alopecia

33 citations, January 2016 in “Indian Journal of Dermatology, Venereology and Leprology”

Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.

Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia

research Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia

42 citations, December 2015 in “International Journal of Clinical Pharmacology and Therapeutics”

The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.

research Antiandrogenic Therapy with Cyproterone Acetate in Female Patients with Androgenetic Alopecia and Acne Vulgaris

5 citations, December 2014 in “Medicine and Pharmacy Reports”

Ciproterone acetate improves hair regrowth and acne in most female patients.

research Female Pattern Alopecia: Current Perspectives

42 citations, August 2013 in “International Journal of Women's Health”

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.