The Pathogenesis of Alopecia Areata in Rodent Models

    June 2003 in “ Journal of Investigative Dermatology Symposium Proceedings ”
    Kevin J. McElwee, Pia Freyschmidt‐Paul, John P. Sundberg, Rolf Hoffmann
    Studysummary This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jidsponline.org →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002
    2. Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata Experimental dermatology · 2001
    3. Current and Potential Agents for the Treatment of Alopecia Areata Current pharmaceutical design · 2001
    4. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    5. Murine Cytomegalovirus Is Not Associated With Alopecia Areata in C3H/HeJ Mice Journal of Investigative Dermatology · 1998
    6. Comparison of Alopecia Areata in Human and Nonhuman Mammalian Species Pathobiology · 1998
    7. Autoantibodies to Hair Follicles in C3H/HeJ Mice With Alopecia Areata-Like Hair Loss Journal of Investigative Dermatology · 1997
    8. Ultrastructural Abnormalities in the Dermal Papillae of Lesional and Clinically Normal Follicles from Alopecia Areata Scalps British Journal of Dermatology · 1996
    9. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994
    10. Stimulation of Hair Growth by Topical Application of FK506, a Potent Immunosuppressive Agent Journal of Investigative Dermatology · 1994
    11. Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata Journal of The American Academy of Dermatology · 1987
    12. Topical Minoxidil (3%) in Extensive Alopecia Areata, Including Long-Term Efficacy Journal of The American Academy of Dermatology · 1987
    13. Alopecia Areata: Pathogenesis And Treatment Journal of the American Academy of Dermatology · 1984
    14. Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 1984

    Related research 7

    1. Oxidative Stress and Alopecia Areata Frontiers in medicine · 2023
    2. Understanding Immune Privilege in an Inducible Mouse Model of Primary Cicatricial Alopecia ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2023
    3. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    4. Familial Aggregation of Alopecia Areata Journal of the American Academy of Dermatology · 2016
    5. Current Status of Treatments for Alopecia Areata 2014
    6. The Immunopathobiology of Lichen Planopilaris [Thesis]. Manchester, UK: The University of Manchester; 2011. · 2011
    7. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005