Sheep IGFBP2 and IGFBP4 Promoter Methylation Regulates Gene Expression and Hair Follicle Development

    July 2022 in “ Electronic Journal of Biotechnology ”
    Yuezhen Tian, Jianwen Du, Xuemei Yang … Kechuan Tian
    Studysummary This study found that the methylation level of the IGFBP4 promoter is negatively correlated with mRNA expression and may serve as an epigenetic marker for wool fineness in Super Merino sheep.
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    Research cited in this study 16

    1. Dynamic Changes of Genomic Methylation Profiles at Different Growth Stages in Chinese Tan Sheep Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · 2021
    2. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    3. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021
    4. DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages Stem cell research & therapy · 2020
    5. Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells BMC complementary medicine and therapies · 2020
    6. Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat Cells · 2020
    7. Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats Frontiers in Genetics · 2020
    8. PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology Experimental Dermatology · 2019
    9. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    10. Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling BMC genomics · 2018
    11. Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered to Overexpress Growth Factors Accelerate Outcomes in Hair Growth The Korean Journal of Physiology and Pharmacology · 2018
    12. Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat Genetica · 2017
    13. Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle Genetica · 2016
    14. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    15. Molecular Conversations and the Development of the Hair Follicle and Basal Cell Carcinoma Cancer Prevention Research · 2010
    16. Insulin-Like Growth Factor 1 and Hair Growth Dermatology Online Journal · 1999