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    Efficacy And Safety Of Low-Dose Oral Minoxidil In The Treatment Of Androgenetic Alopecia: A Literature Review

    Filip Kieloch, Agnieszka Fitas, Karol Kanon … Karolina Dębek-Kalinowska
    Studysummary This study found that low-dose oral minoxidil (≤5 mg/day) effectively increased hair number and diameter in men and women with androgenetic alopecia, and was generally well-tolerated with mostly mild adverse effects, although serious complications were rare and associated mainly with pre-existing heart conditions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 32

    1. Dutasteride for the Treatment of Androgenetic Alopecia: An Updated Review Dermatology · 2024
    2. Evaluation of Pericardial Effusions in Alopecia Patients on Low-Dose Oral Minoxidil Therapy Journal of Drugs in Dermatology · 2024
    3. Oral Minoxidil Versus Topical Minoxidil for Male Androgenetic Alopecia JAMA dermatology · 2024
    4. Low-Dose Oral Minoxidil for Alopecia: A Comprehensive Review Skin appendage disorders · 2023
    5. Randomized Clinical Trial of Low-Dose Oral Minoxidil for the Treatment of Female Pattern Hair Loss: 0.25 mg Versus 1 mg Journal of The American Academy of Dermatology · 2022
    6. Role Of Oral Minoxidil In Patterned Hair Loss Indian Dermatology Online Journal · 2022
    7. A Randomized Clinical Trial on Therapeutic Effects of 0.25 mg Oral Minoxidil Tablets on Treatment of Female Pattern Hair Loss Dermatologic Therapy · 2021
    8. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
    9. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    10. Efficacy and Safety of Oral Minoxidil in Female Androgenetic Alopecia Dermatologic Therapy · 2020
    11. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    12. Female Pattern Hair Loss: A Comprehensive Review Dermatologic Therapy · 2020
    13. Low-Dose Oral Minoxidil for Female Pattern Hair Loss: A Unicenter Descriptive Study of 148 Women Skin appendage disorders · 2020
    14. Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation Journal of The American Academy of Dermatology · 2019
    15. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    16. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    17. Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia Journal of The American Academy of Dermatology · 2019
    18. Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone International Journal of Dermatology · 2017
    19. Classification of Male-Pattern Hair Loss International Journal of Trichology · 2017
    20. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    21. Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia Dermatologic Therapy · 2014
    22. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    23. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    24. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    25. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    26. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009
    27. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    28. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    29. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    30. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999
    31. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    32. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998

    Related research 2

    1. Contact Dermatitis Caused by Topical Minoxidil: Allergy or Just Irritation Acta Dermato Venereologica · 2025
    2. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023