Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles

    September 2021 in “ Colloids and surfaces. B, Biointerfaces ”
    Ricardo Ferreira‐Nunes, Marcílio Cunha-Filho, Guilherme M. Gelfuso
    Studysummary This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.
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    Research cited in this study 9

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    2. Spironolactone for Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
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    5. Hormonal Treatment of Acne Vulgaris: An Update Clinical, Cosmetic and Investigational Dermatology · 2016
    6. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    7. Hair Follicles as a Target Structure for Nanoparticles Journal of innovative optical health sciences/Journal of innovation in optical health science · 2015
    8. New Developments in Our Understanding of Acne Pathogenesis and Treatment Experimental dermatology · 2009
    9. Sexual Hormones in Human Skin Hormone and metabolic research · 2007