Effect of a Sphingolipid-Mimetic Compound on Hair Growth Promotion: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    November 2019 in “ Journal of Cosmetic Dermatology ”
    Weon Ju Lee, Chihyeon Sohng, Jun Young Kim … Seok‐Jong Lee
    Studysummary This study found that applying a 1% BOI lotion improved hair density and thickness in patients with mild pattern hair loss over six months.
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    Research cited in this study 23

    1. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    2. Excellent Response to Mesotherapy as Adjunctive Treatment in Male Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    3. Minoxidil in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2018
    4. Study of the Efficacy of Carboxytherapy in Alopecia Journal of Cosmetic Dermatology · 2018
    5. Promotion of Hair Growth by Newly Synthesized Ceramide Mimetic Compound Biochemical and biophysical research communications · 2017
    6. A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia Journal of Dermatological Treatment · 2017
    7. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    8. Sexual Side Effects of 5-Alpha-Reductase Inhibitors Finasteride and Dutasteride: A Comprehensive Review Dermatology Online Journal · 2017
    9. Platelet-Rich Plasma in Androgenic Alopecia: Indications, Technique, and Potential Benefits Journal of Oral and Maxillofacial Surgery · 2016
    10. Superiority of Dutasteride Over Finasteride in Hair Regrowth and Reversal of Miniaturization in Men With Androgenetic Alopecia: A Randomized Controlled Open-Label, Evaluator-Blinded Study Indian Journal of Dermatology, Venereology and Leprology · 2016
    11. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    12. Alkaline Ceramidase 1 Is Essential for Mammalian Skin Homeostasis and Regulating Whole-Body Energy Expenditure The Journal of Pathology · 2016
    13. Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth Annals of Dermatology · 2016
    14. Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy Indian Journal of Dermatology · 2015
    15. Ceramide Synthase 4 Deficiency in Mice Causes Lipid Alterations in Sebum and Results in Alopecia Biochemical Journal · 2014
    16. Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial Evidence-based Complementary and Alternative Medicine · 2014
    17. Comparative Effectiveness of Finasteride vs Serenoa Repens in Male Androgenetic Alopecia: A Two-Year Study International Journal of Immunopathology and Pharmacology · 2012
    18. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012
    19. The Efficacy and Safety of 17α-Estradiol (Ell-Cranell Alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study Annals of Dermatology · 2012
    20. Integral Hair Lipid in Human Hair Follicle Journal of dermatological science · 2011
    21. Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Regrowth in Testosterone-Treated Mice Phytotherapy Research · 2011
    22. Hair Growth Promoting Effect of Zizyphus Jujuba Essential Oil Food and Chemical Toxicology · 2010
    23. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003

    Related research 6

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    2. Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp Journal of Cosmetic Dermatology · 2022
    3. Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss Journal of Dermatology · 2020
    4. Treatments of Hereditary Hair Loss (Alopecia) 2018
    5. The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis International Journal of Dermatology · 2008
    6. Treatment of Hair Loss The New England Journal of Medicine · 1999