Age-Related Downregulation of Dihydrotestosterone-Inactivating Enzymes in Human Scalp Sebaceous Glands

    April 2026 in “ Inflammation and Regeneration ”
    Yasuaki Ikuno, Yukie Kande, Akiko Arakawa … Hayato Naka-Kaneda
    Studysummary This study found that androgen inactivation pathways in scalp sebaceous glands change with age, specifically noting that AKR1C expression, including AKR1C4 previously thought liver-specific, declines with age and is sex dependent, which could impact hair follicle health during aging.
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    Research cited in this study 23

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