Increased Prevalence of Insulin Resistance and Metabolic Syndrome in Men With Early-Onset Androgenetic Alopecia: A Case-Control Study

November 2025 in “ Journal of Cosmetic Dermatology ”

Orkun Erden, Ahu Yorulmaz

androgenetic alopecia insulin resistance metabolic syndrome HOMA-IR triglyceride fasting insulin waist circumference AGA IR MetS

Studysummary This study reported that young men with early-onset androgenetic alopecia have a higher prevalence of insulin resistance and metabolic syndrome compared to controls, suggesting that AGA may indicate underlying metabolic disturbances.

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This study examined the link between early-onset androgenetic alopecia (AGA) and metabolic disorders in young men, involving 200 participants (100 with AGA and 100 controls). It found that men with AGA had significantly higher waist circumference and insulin levels, with 18% having insulin resistance (IR) compared to 4% of controls, and 21% having metabolic syndrome (MetS) compared to 9% of controls. The results suggest that early-onset AGA may be a clinical marker for underlying metabolic disturbances, highlighting the need for metabolic risk screening in these individuals to enable preventive interventions.

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Research cited in this study

18 / 18 results

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