Gellan Gum-Based Hydrogels Support the Recreation of the Dermal Papilla Microenvironment

    April 2023 in “ Biomaterials advances
    Carla M. Abreu, Manuela E.L. Lago, Joana Pires, Rui L. Reis, Lucília P. da Silva, Alexandra P. Marques
    Image of study
    TLDR Gellan gum hydrogels help recreate the environment needed for hair growth cell function.
    The study investigated the use of gellan gum-based hydrogels to recreate the dermal papilla (DP) microenvironment, a key factor in hair growth. The researchers found that stiffer hydrogels (1.25% vs 0.75% gellan gum) improved DP cell inductivity in short term cultures and supported basic hair morphogenesis events in a human skin model. The hydrogels were biofunctionalized with collagen IV or fibronectin-related peptides, and the type of peptide and gellan gum amount independently modulated the type and quantity of deposited extracellular matrix proteins. The study concluded that gellan gum-based hydrogels could be a promising tool for hair follicle regeneration and the evaluation of new candidate drugs for hair growth.
    Discuss this study in the Community →

    Research cited in this study

    27 / 27 results

    Related Community Posts Join

    1 / 1 results

      community Theory And Observation: Why Being Bald Can Really Work

      in Shaved/buzzed  88 upvotes 9 months ago
      The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

    Similar Research

    5 / 74 results