Efficacy of Autologous Growth Factor Concentrate Versus Platelet-Rich Plasma Injection in Patients With Androgenetic Alopecia Receiving Topical Minoxidil: A Randomized Controlled Trial

    Shini Choubey, Laxman Besra, Nithya Satish, C. R. Srinivas
    Studysummary This study found that growth factor concentrate injections combined with topical minoxidil in androgenetic alopecia patients led to similar hair regrowth outcomes as platelet-rich plasma, with lower reported pain.
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    Research cited in this study 22

    1. Clinical and Trichoscopic Analysis of PRP Versus GFC for Male and Female Pattern Hair Loss Dermatologic Surgery · 2025
    2. Platelet-Rich Plasma Effectiveness in Treating Androgenetic Alopecia: A Comprehensive Evaluation Cureus · 2025
    3. On The Diversity And Effectiveness Of Therapy Methods For Androgenetic Alopecia A I Burnasyan Federal Medical Biophysical Center Clinical Bulletin · 2024
    4. Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination in the Treatment of Men with Androgenetic Alopecia Scholars Journal of Applied Medical Sciences · 2024
    5. Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study Journal of Cosmetic Dermatology · 2024
    6. The Latest Reports on Androgenetic Alopecia Quality in Sport · 2024
    7. Androgenetic Alopecia in Men: An Update on Genetics Indian Journal of Dermatology · 2024
    8. Effectiveness of Autologous Growth Factor Concentrates Combined With Topical Minoxidil in Patients of Androgenic Alopecia MRIMS journal of health sciences · 2024
    9. The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology Skin appendage disorders · 2024
    10. Meta-Analysis on the Efficacy of Platelet-Rich Plasma in Patients with Androgenetic Alopecia International journal of trichology · 2023
    11. Low-Dose Oral Minoxidil in the Treatment of Alopecia: Evidence and Experience-Based Consensus Statement of Indian Experts International Journal of Trichology · 2023
    12. Efficacy of Autologous Platelet-Rich Plasma Therapy Versus Topical Minoxidil in Men With Moderate Androgenetic Alopecia: A Randomized Open-Label Trial Journal of Dermatological Treatment · 2023
    13. Growth Factor Concentrate Therapy for Management of Hair Loss: A Prospective, Real-World Study International Journal of Research in Dermatology · 2022
    14. Autologous Platelet-Rich Plasma Treatment for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Clinical Trials on Patient Safety, Efficacy and Outcomes Plastic and Reconstructive Surgery · 2022
    15. Change in Hair Growth-Related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-Alpha Reductase Inhibitors – Dutasteride and Finasteride – in the Presence of Testosterone Singapore Medical Journal · 2021
    16. Autologous Concentrated Growth Factors Combined With Topical Minoxidil for the Treatment of Male Androgenetic Alopecia: A Randomized Controlled Clinical Trial Facial plastic surgery & aesthetic medicine · 2020
    17. Serum Levels of Androgen-Associated Hormones Are Correlated with Curative Effect in Androgenic Alopecia in Young Men Medical Science Monitor · 2018
    18. Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia Skin appendage disorders · 2017
    19. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016
    20. Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology Journal of Investigative Dermatology · 2013
    21. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    22. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002