Autologous Platelet Concentrates for the Treatment of Primary Cicatricial Alopecia: A Systematic Review

    January 2026 in “ Dermatologic Therapy ”
    Zhen-Yin Ma, Li‐Ping Liu, Y Zhang … Yun‐Wen Zheng
    Studysummary This study suggests that autologous platelet concentrates may improve inflammatory activity, disease control, and hair regrowth in primary cicatricial alopecia, but the evidence is limited by small sample sizes and study quality.
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    Research cited in this study 22

    1. Single-Cell Sequencing Combined With Spatial Transcriptomics Reveals the Characteristics of Follicle-Targeted Inflammation Patterns in Primary Cicatricial Alopecia Cell & Bioscience · 2025
    2. Evaluating Anti-Inflammatory Potential of Platelet-Rich Plasma in Scarring Alopecia: A Systematic Review Journal of Drugs in Dermatology · 2024
    3. Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study Journal of Cosmetic Dermatology · 2024
    4. Effectiveness of Injectable Platelet-Rich Fibrin Therapy in Alopecia and Facial Rejuvenation: A Systematic Review Cureus · 2024
    5. Platelet-Rich Plasma as a New and Successful Treatment for Lichen Planopilaris: A Controlled Blinded Randomized Clinical Trial Journal of cosmetic dermatology · 2024
    6. Concentrated Growth Factor Therapy as Cosmetic Treatment in Discoid Lupus Erythematosus Journal of dermatology · 2024
    7. A Systematic Review And Bayesian Network Meta-Analysis Of Medical Therapies For Lichen Planopilaris Dermatology · 2023
    8. Halting the Progression of Cicatricial Alopecia with Injectable Platelet-Rich Fibrin International journal of trichology · 2023
    9. Platelet-Rich Plasma in Alopecia Areata and Primary Cicatricial Alopecias: A Systematic Review Frontiers in Medicine · 2022
    10. Transitory Hair Growth Using Platelet-Rich Plasma Therapy in Stabilized Central Centrifugal Cicatricial Alopecia Dermatologic therapy · 2022
    11. Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma Journal of Drugs in Dermatology · 2022
    12. The Role of Platelet-Rich Plasma Therapy in Refractory Folliculitis Decalvans JAAD Case Reports · 2021
    13. Use of Platelet-Rich Plasma in Lichen Planopilaris and Its Variants: A Retrospective Case Series Demonstrating Treatment Tolerability Without Koebnerization Journal of The American Academy of Dermatology · 2020
    14. Platelet-Rich Plasma for Treatment-Resistant Frontal Fibrosing Alopecia: A Case Report Dermatologic Therapy · 2019
    15. Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study Skin appendage disorders · 2019
    16. Use of Platelet-Rich Plasma in Cicatricial Alopecia Dermatologic Surgery · 2018
    17. Platelet-Rich Plasma for the Treatment of Lichen Planopilaris Journal of the American Academy of Dermatology · 2018
    18. Platelet-Rich Plasma as a Novel Treatment for Lichen Planopillaris Dermatologic therapy · 2016
    19. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    20. Primary Cicatricial Alopecia: Diagnosis and Treatment Canadian Medical Association Journal · 2013
    21. The Pathogenesis of Primary Cicatricial Alopecias The American Journal of Pathology · 2010
    22. Management of Primary Cicatricial Alopecias: Options for Treatment British Journal of Dermatology · 2008