Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia

    January 2019 in “ The American Journal of Dermatopathology ”
    Mariya Miteva, David Castillo, Samar Sabiq
    Studysummary This study discovered that adipose tissue infiltration at the isthmus level appears significantly more often in frontal fibrosing alopecia cases compared to controls, suggesting a potential role in the condition's pathology.
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    Research cited in this study 11

    1. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018
    2. The Arrector Pili Muscle: The Bridge Between the Follicular Stem Cell Niche and the Interfollicular Epidermis Anatomical Science International · 2016
    3. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center International Journal of Trichology · 2016
    4. Finasteride-Mediated Hair Regrowth and Reversal of Atrophy in a Patient with Frontal Fibrosing Alopecia JAAD case reports · 2015
    5. The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015
    6. Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link Skin Appendage Disorders · 2015
    7. Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia British Journal of Dermatology · 2014
    8. Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients Journal of The American Academy of Dermatology · 2014
    9. Expression of Snail1 in the Fibrotic Dermis of Postmenopausal Frontal Fibrosing Alopecia: Possible Involvement of an Epithelial-Mesenchymal Transition and a Review of Japanese Patients British Journal of Dermatology · 2010
    10. Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study International Journal of Dermatology · 2006
    11. Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris Journal of the American Academy of Dermatology · 1997

    Related research 3

    1. Histomorphological, Histochemical and Histoenzymic Studies on the Dermis of Skin of Goat (Capra Hircus) Indian Journal of Animal Research · 2021
    2. Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia The American Journal of Dermatopathology · 2019
    3. Defining Dermal Adipose Tissue Experimental Dermatology · 2014