Patient-Reported Satisfaction With Hair Regrowth in a Study of Ritlecitinib in Alopecia Areata: Results From ALLEGRO-2b/3

    June 2024 in “ Dermatology ”
    Rodney Sinclair, Ernest H. Law, Xingqi Zhang … Natasha Atanaskova Mesinkovska
    Studysummary This study found that patients receiving active ritlecitinib doses reported greater satisfaction with hair growth compared to placebo, with high agreement observed between clinician evaluations of scalp hair improvement and patient satisfaction through week 48.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 17

    1. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    2. The Relationship Between Patient-Reported Severity of Hair Loss and Health-Related Quality of Life and Treatment Patterns Among Patients with Alopecia Areata Dermatology and Therapy · 2022
    3. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    4. Patient Perspectives of the Social, Emotional and Functional Impact of Alopecia Areata: A Systematic Literature Review Dermatology and Therapy · 2021
    5. Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan Dermatology and therapy · 2021
    6. The Role of Patients in Alopecia Areata Endpoint Development: Understanding Physical Signs and Symptoms Journal of Investigative Dermatology Symposium Proceedings · 2020
    7. ‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata Journal of Patient-Reported Outcomes · 2020
    8. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    9. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019
    10. Targeting the Janus Kinase Family in Autoimmune Skin Diseases Frontiers in Immunology · 2019
    11. Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata Drug design, development and therapy · 2018
    12. Multiplex Matrix Network Analysis of Protein Complexes in the Human TCR Signalosome Science Signaling · 2016
    13. The Autoimmune Basis of Alopecia Areata: A Comprehensive Review Autoimmunity reviews · 2014
    14. Alteration in Hair Texture Following Regrowth in Alopecia Areata Archives of Dermatology · 2011
    15. A Case of Widespread Non-Pigmented Hair Regrowth in Diffuse Alopecia Areata Australasian Journal of Dermatology · 2007
    16. Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007
    17. Persistent Depigmented Regrowth After Alopecia Areata Journal of the American Academy of Dermatology · 2002

    Related research 3

    1. Revitalizing Hair Growth: A New Regimen Utilizing Growth Factor Concentrate for Hair Loss Treatment Cureus · 2024
    2. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018