The Role of Patients in Alopecia Areata Endpoint Development: Understanding Physical Signs and Symptoms

The study titled "The Role of Patients in Alopecia Areata Endpoint Development: Understanding Physical Signs and Symptoms" conducted 30 semistructured interviews with adult (n = 25) and adolescent (n = 5) patients suffering from severe or very severe Alopecia Areata (AA), a chronic autoimmune disease causing hair loss. The study found that scalp hair loss was the most significant symptom for 90% of the patients, with 77% (n = 23) naming it as the most bothersome. Other bothersome symptoms included eyebrow, eyelash, nose, body, and facial hair loss, as well as eye irritation and nail damage. The study concluded that the primary objective for new AA treatments should be meaningful improvement in scalp hair growth.