Acne Syndromes and Mosaicism

November 2021 in “ Biomedicines ”

Sumer Baroud, Jim Wu, Christos C. Zouboulis

Studysummary This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function

97 citations , September 2016 in “Reviews in Endocrine and Metabolic Disorders”

This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.

research Acne Tarda and Male-Pattern Baldness Unmasking Primary Ovarian Insufficiency: A Case and Review

4 citations , January 2014 in “Dermatology”

This case report details a woman with autoimmune primary ovarian insufficiency linked to hormonal contraception discontinuation, who achieved pregnancy through ovarian stimulation and in vitro fertilization despite typically low fertility in such conditions.

research Acne as a Chronic Systemic Disease

71 citations , November 2013 in “Clinics in Dermatology”

This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

research Emerging Concepts About Prenatal Genesis, Aberrant Metabolism, and Treatment Paradigms in Polycystic Ovary Syndrome

25 citations , June 2012 in “Endocrine”

This review discusses emerging concepts in PCOS from the AEPCOS 2010 meeting and reports no clinical findings; it suggests that the transition of care in congenital adrenal hyperplasia could inform PCOS adolescent care.

research Pathways to Inflammation: Acne Pathophysiology

68 citations , May 2011 in “European Journal of Dermatology”

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

research Polycystic Ovary Syndrome and Acne

10 citations , January 2011 in “Skin therapy letter”

This review discusses treatments for acne in women with polycystic ovary syndrome due to androgen excess and reports no new clinical results.

research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

99 citations , December 2010 in “Journal of The European Academy of Dermatology and Venereology”

This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.

research Anti-Androgen Treatments for Hirsutism and Acne in Women of Childbearing Age

24 citations , January 2010 in “Annales d'endocrinologie”

This review discusses treatment options for hirsutism in women of childbearing age, focusing on the use of contraceptives, CPA, spironolactone, and third-line therapies, and reports no clinical results.

research New Developments in Our Understanding of Acne Pathogenesis and Treatment

466 citations , June 2009 in “Experimental dermatology”

This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.

research Role of FGFR2-Signaling in the Pathogenesis of Acne

63 citations , May 2009 in “Dermato-endocrinology”

This review explores the role of FGFR2b-signaling in the pathogenesis of acne, highlighting its influence on sebaceous gland physiology and the effects of anti-acne agents like isotretinoin.

research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations , February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.

research Nevus Comedonicus Syndrome: A Case Associated With Multiple Basal Cell Carcinomas and a Rudimentary Toe

38 citations , June 2005 in “International Journal of Dermatology”

This case report describes a 28-year-old man with widespread pigmented basal cell carcinomas and recurrent infections that were challenging to control, associated with nevus comedonicus and a rudimentary toe.

research Androgen Action on Human Skin – From Basic Research to Clinical Significance

147 citations , October 2004 in “Experimental dermatology”

This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.

research Acne and Sebaceous Gland Function

463 citations , September 2004 in “Clinics in dermatology”

This review discusses the development, function, and complex roles of sebaceous glands in acne and suggests future acne treatments should target inflammation and lipid production; it reports no new clinical results.

research Update and Future of Systemic Acne Treatment

117 citations , January 2003 in “Dermatology”

This review discusses various treatments for moderate-to-severe acne, highlighting antibiotics, oral isotretinoin, and hormonal therapies, with a focus on resistance and emerging treatment options but reports no new clinical results.

research The SAHA Syndrome: Overview and Classification

70 citations , January 2000 in “Hormone Research in Paediatrics”

This article reviews the characteristics and classification of SAHA syndrome and its relationship with other conditions, without presenting new clinical findings.

research Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne

186 citations , July 1998 in “Journal of Cutaneous Medicine and Surgery”

This study found that shorter CAG-repeat lengths in the androgen receptor may be associated with the development of androgen-mediated skin disorders like androgenetic alopecia, acne, and hirsutism in both men and women.

research Acneiform Dermatoses

45 citations , January 1998 in “Dermatology”

This review examines acneiform eruptions, often drug-induced, highlighting that they differ from acne vulgaris in causes and characteristics, with no new clinical results reported.

research Keratinocyte Growth Factor Is an Important Endogenous Mediator of Hair Follicle Growth, Development, and Differentiation. Normalization of the Nu/Nu Follicular Differentiation Defect and Amelioration of Chemotherapy-Induced Alopecia.

219 citations , July 1995 in “PubMed”

This study found that recombinant keratinocyte growth factor (rKGF) stimulated hair growth and provided a protective effect against alopecia in murine models, suggesting its role in hair follicle development and regeneration.