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GlossaryGenetic Mosaicism (Mosaicism)

presence of different genetic cell lines within one individual

Genetic Mosaicism, also known simply as Mosaicism, refers to the presence of two or more genetically distinct cell lines within the same individual, originating from a single fertilized egg. This can result from mutations during cell division in early development, leading to some cells having different genetic makeup than others. This phenomenon can affect various tissues and organs, potentially leading to conditions like segmental vitiligo or certain forms of alopecia.

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Acne Syndromes and Mosaicism

research Acne Syndromes and Mosaicism

1 citations, November 2021 in “Biomedicines”

Understanding how acne develops in different diseases could lead to new treatments.

Becker's Nevus Associated with Chromosomal Mosaicism and Congenital Adrenal Hyperplasia

research Becker's Nevus Associated with Chromosomal Mosaicism and Congenital Adrenal Hyperplasia

32 citations, April 1994 in “Journal of the American Academy of Dermatology”

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

research CPC14 Blaschko-Linear Trichoepitheliomas: Unveiling Type 1 Segmental Mosaicism

June 2025 in “British Journal of Dermatology”

A rare skin condition in a boy is likely due to a specific genetic mutation pattern.

research Porokeratotic Adnexal Ostial Nevus: A Paradigm of Cutaneous Mosaicism

February 2022 in “Authorea (Authorea)”

PAON shows skin patterns due to genetic mosaicism.

research Occurrence of Klinefelter Syndrome Mosaic 45,X/46,XY/47,XXY/48,XXYY/48,XXXY and Primary Hyperparathyroidism

March 2021 in “AACE clinical case reports”

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

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