Epidermal Stem Cells: Practical Perspectives and Potential Uses

    April 2009 in “ British Journal of Dermatology ”
    Ossama Abbas, Meera Mahalingam
    Studysummary This review discusses the potential markers for identifying and studying stem cells in the epidermis and hair follicles, highlighting their role in understanding skin disease pathogenesis and expanding therapeutic options, but reports no new findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia British Journal of Dermatology · 2009
    2. Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts Journal of cutaneous pathology · 2008
    3. Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200 Journal of Investigative Dermatology · 2007
    4. Hair Follicle Stem Cells: Walking the Maze European Journal of Cell Biology · 2007
    5. Scratching the Surface of Skin Development Nature · 2007
    6. The Cell-Surface Marker MTS24 Identifies a Novel Population of Follicular Keratinocytes With Characteristics of Progenitor Cells Development · 2006
    7. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    8. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005
    9. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    10. Melanocyte Stem Cell Maintenance and Hair Graying Cell · 2005
    11. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    12. Location and Phenotype of Human Adult Keratinocyte Stem Cells of the Skin Differentiation · 2004
    13. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    14. Gene Delivery to the Hair Follicle Journal of Investigative Dermatology Symposium Proceedings · 2003
    15. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    16. Immunofluorescence Analysis of the Basement Membrane Zone Components in Human Anagen Hair Follicles Experimental Dermatology · 2003
    17. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    18. P63 Expression in Normal Skin and Common Cutaneous Carcinomas Journal of Cutaneous Pathology · 2002
    19. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    20. Keratin 19 as a Biochemical Marker of Skin Stem Cells In Vivo and In Vitro: Localization and Variation with Age and Culture Stage Journal of Cell Science · 1996

    Related research 5

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    4. Epidermal Stem Cells in the Skin Chinese bulletin of Life sciences · 2008
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006