Laminin α5 in the Keratinocyte Basement Membrane Is Required for Epidermal–Dermal Intercommunication

    May 2016 in “ Matrix Biology ”
    Jeannine Wegner, Karin Loser, Gunita Apsite … Lydia Sorokin
    Studysummary This study found that the absence of laminin α5 in adult mice's epidermal basement membrane led to keratinocyte hyperproliferation and immune cell changes, affecting hair follicle development through altered growth factor expression.
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    Research cited in this study 3

    1. Development and Homeostasis of the Sebaceous Gland Seminars in Cell & Developmental Biology · 2012
    2. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009
    3. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005