Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells

    December 2005 in “ ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation ”
    Manabu Ohyama
    Studysummary This study found that bulge cells marked by CD200+ in human hair follicles show high colony-forming efficiency, suggesting successful enrichment of keratinocyte stem cells.
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    Research cited in this study 10

    1. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    2. Gene Delivery to the Hair Follicle Journal of Investigative Dermatology Symposium Proceedings · 2003
    3. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    4. Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin The FASEB Journal · 2003
    5. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    6. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    7. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    8. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    9. Differential Epithelial Outgrowth of Plucked and Microdissected Human Hair Follicles in Explant Culture Archives of Dermatological Research · 1996
    10. Characterization of Hair Follicle Bulge in Human Fetal Skin: The Human Fetal Bulge Is a Pool of Undifferentiated Keratinocytes Journal of Investigative Dermatology · 1995