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GlossaryColony-Forming Efficiency

measure of cells' ability to proliferate and form colonies

Colony-Forming Efficiency (CFE) is a measure used in cell biology to determine the proportion of cells in a given population that are capable of proliferating and forming colonies. It is often used to assess the health and viability of stem cells or other proliferative cells, such as those involved in hair follicle regeneration. CFE is calculated by dividing the number of colonies formed by the number of cells initially plated, providing insight into the regenerative potential of the cell sample.

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Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

research Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

16 citations, January 2007 in “Dermatology”

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

research Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells

January 2007 in “The Year book of dermatology”

Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.

research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes

2 citations, December 2016 in “Experimental cell research”

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Short-Term Rho-Associated Kinase Inhibitor Treatment Accelerates Primary Keratinocyte Growth Without Affecting the Stem Cell Population

research Short-Term Rho-Associated Kinase Inhibitor Treatment Accelerates Primary Keratinocyte Growth Without Affecting the Stem Cell Population

November 2022 in “Journal of Investigative Dermatology”

Short-term treatment with ROCKi increases skin cell growth without changing stem cell features.

research Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells

550 citations, December 2005 in “The Journal of clinical investigation/The journal of clinical investigation”

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

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community Horrible news, Stemson Therapeutics has shut down

in Technology 193 upvotes 2 months ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Oral Fin+Min: Digital microscope scalp review - Day 0 Vs 3 Months

in Progress Pictures 1293 upvotes 4 days ago

A user used oral finasteride and minoxidil for hair loss, seeing new hair growth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 18 upvotes 4 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community A Summary of the Latest Research regarding PFS, and How Supplementing Allopregnanolone Might Protect Against It

in Chat 6 upvotes 11 months ago

Post Finasteride Syndrome (PFS) may result from epigenetic changes and gut microbiota alterations. Supplementing with Allopregnanolone might protect against these adverse effects.

community I just made 60x of 5mg minoxidil sugar cubes

in Minoxidil 1331 upvotes 3 months ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

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