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    Glossary Colony-Forming Efficiency

    measure of cells' ability to proliferate and form colonies

    Colony-Forming Efficiency (CFE) is a measure used in cell biology to determine the proportion of cells in a given population that are capable of proliferating and forming colonies. It is often used to assess the health and viability of stem cells or other proliferative cells, such as those involved in hair follicle regeneration. CFE is calculated by dividing the number of colonies formed by the number of cells initially plated, providing insight into the regenerative potential of the cell sample.

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    1. Ageing and colony-forming efficiency of human hair follicle keratinocytes Experimental Dermatology · 2013 · 9 citations
    2. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    3. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011 · 61 citations
    4. Bulge cells of human hair follicles: segregation, cultivation and properties Colloids and Surfaces B: Biointerfaces · 2006 · 27 citations
    5. Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces Stem cells international · 2015 · 23 citations
    6. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007 · 16 citations
    7. Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes Experimental cell research · 2016 · 2 citations
    8. 557 Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth without affecting the characteristics of the stem cell population Journal of Investigative Dermatology · 2022
    9. Characterization and isolation of stem cell–enriched human hair follicle bulge cells ˜The œYear book of dermatology · 2007
    10. Enrichment of human hair follicle stem cells by adhering to typeIVcollagen 2006
    11. In vitro culture of murine fetal epidermal stem cell and its relationship with the regeneration of hair follicle Zhonghua shaoshang zazhi · 2003
    12. Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff Journal of cosmetics, dermatological sciences and applications · 2013 · 2 citations
    13. The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells Development · 2006 · 207 citations
    14. In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing Cytotherapy · 2015 · 52 citations
    15. Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis Stem Cell Research & Therapy · 2015 · 14 citations
    16. The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells Cell proliferation · 2023 · 5 citations
    17. 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor Journal of Investigative Dermatology · 2022
    18. 25 Years of Epidermal Stem Cell Research Journal of Investigative Dermatology · 2012 · 55 citations
    19. Transcriptional profiling of putative human epithelial stem cells BMC Genomics · 2008 · 16 citations
    20. O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion 2023
    21. Screening and culture of human vaginal mucosa stem cells Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu · 2008
    22. 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing Stem Cell Research & Therapy · 2020 · 17 citations
    23. Unlocking finasteride's potential via carboxymethyl-β-cyclodextrin inclusion complex for androgenic alopecia Carbohydrate Polymer Technologies and Applications · 2025
    24. Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors Stem cells translational medicine · 2016 · 17 citations
    25. Induced Mammary Epithelial Cell-Derived Extracellular Vesicles Promote the Repair of Skin Trauma International Journal of Molecular Sciences · 2025
    26. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    27. Impaired Keratinocyte Proliferative and Clonogenic Potential in Transgenic Mice Overexpressing 14-3-3σ in the Epidermis Journal of Investigative Dermatology · 2011 · 15 citations
    28. A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics ACS Biomaterials Science & Engineering · 2024
    29. Hair follicle stem cell cultures reveal self‐organizing plasticity of stem cells and their progeny The EMBO Journal · 2016 · 61 citations
    30. AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response Frontiers in Cell and Developmental Biology · 2026 · 1 citations