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    Glossary PHLDA1

    gene linked to hair follicle development and hair loss

    PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1) is a gene that encodes a protein involved in cell survival and apoptosis (programmed cell death). In the context of hair biology, PHLDA1 has been linked to hair follicle development and cycling, and its expression is often studied in relation to conditions like alopecia (hair loss).

    Research 7 of 44

    1. Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression Journal of Cutaneous Pathology · 2014 · 47 citations
    2. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    3. Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges BioEssays · 2014 · 106 citations
    4. Clinicopathologic study of 90 cases of trichofolliculoma Journal of the European Academy of Dermatology and Venereology · 2016 · 19 citations
    5. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors Annals of Dermatology · 2014 · 8 citations
    6. Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg–like Cells, and Common EGFR Somatic Mutations The American Journal of Surgical Pathology · 2021 · 4 citations
    7. Characterization and isolation of stem cell–enriched human hair follicle bulge cells ˜The œYear book of dermatology · 2007
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