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    Glossary PHLDA1

    gene linked to hair follicle development and hair loss

    PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1) is a gene that encodes a protein involved in cell survival and apoptosis (programmed cell death). In the context of hair biology, PHLDA1 has been linked to hair follicle development and cycling, and its expression is often studied in relation to conditions like alopecia (hair loss).

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    Research 30 of 43

    1. Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression Journal of Cutaneous Pathology · 2014 · 47 citations
    2. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    3. Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges BioEssays · 2014 · 106 citations
    4. Clinicopathologic study of 90 cases of trichofolliculoma Journal of the European Academy of Dermatology and Venereology · 2016 · 19 citations
    5. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors Annals of Dermatology · 2014 · 8 citations
    6. Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg–like Cells, and Common EGFR Somatic Mutations The American Journal of Surgical Pathology · 2021 · 4 citations
    7. Characterization and isolation of stem cell–enriched human hair follicle bulge cells ˜The œYear book of dermatology · 2007
    8. Hair follicle stem cells: A new arena International Journal of Trichology · 2011 · 1 citations
    9. Immunohistochemistry of Canine Hair Follicle Stem Cells (cHFSCs) by using CK15 and CK19 Journal of animal research · 2020
    10. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    11. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis Cell Stem Cell · 2016 · 106 citations
    12. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing Science Advances · 2021 · 66 citations
    13. Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair Stem Cell Reviews and Reports · 2016 · 24 citations
    14. The clinicopathological spectrum of trichoepitheliomas: a retrospective descriptive study International Journal of Dermatology · 2015 · 6 citations
    15. Regenerative potential of CD200- subpopulations of hair follicle bulge Frontiers in Cell and Developmental Biology · 2026
    16. Obtenção e caracterização das células-tronco do folículo piloso de fetos caninos 2016
    17. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007 · 16 citations
    18. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020 · 3 citations
    19. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020 · 2 citations
    20. Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome 2025
    21. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020
    22. Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX2 and SOX9 in the human hair follicle Experimental Dermatology · 2015 · 33 citations
    23. Adipogenic Differentiation of Canine Hair Follicle Stem Cells (cHFSCs) Indian Journal of Animal Research · 2022
    24. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    25. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015 · 232 citations
    26. Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia International Journal of Molecular Sciences · 2019 · 88 citations
    27. Therapeutic Potential of Stem Cells in Follicle Regeneration Stem Cells International · 2018 · 45 citations
    28. Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy Nature Communications · 2019 · 32 citations
    29. A systematic summary of survival and death signalling during the life of hair follicle stem cells Stem Cell Research & Therapy · 2021 · 31 citations
    30. Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature Lupus Science & Medicine · 2019 · 17 citations